Thursday, November 28, 2019

Nike And Asian Labour Essays - Business, Nike, Inc., Fashion

Nike And Asian Labour There has been much debate and controversy recently concerning Nike's Asian labour practices. This is a very complex issue and one that is a long way from being solved. It is very difficult to determine which side of this argument to defend, as both sides acknowledge the facts, yet put a completely different spin on them. Do you believe Nike's critics who say they're exploiting workers? Or, do you believe Nike when they say that they are giving workers in these countries wonderful opportunities to raise their standard of living? The consensus answer to this question by all sides seems to be that Nike is improving but still has a ways to go. Nike's Asian ties can be traced back to the birth of the company. The CEO, chairman of the board of directors, and co-founder, Phil Knight, wrote his masters thesis at Stanford University in the 1960's on the prospects for using Asian labor to produce goods cheaper and more effectively. In order to incorporate this plan in to Nike's business structure, a partnership was set up with a Japan based company called Tiger Sports. Tiger Sports would manufacture shoes for Nike in Asia then shipped them to the United States to sell. In the 1980's however, this aspect of Nike's partnership with Tiger Sports was dissolved, and Nike was forced to expand production from the United States to countries such as Taiwan and Korea where their products could be manufactured at the same relatively low cost that Nike enjoyed through the Tiger Sports partnership. Over the last five of years, however, the production numbers for these countries have been decreasing at an alarming rate due to the fact that their economies expanded at a very rapid pace. This, in turn, caused the cost of labour to increase dramatically, and therefore Nike could no longer produce their product as efficiently as before. In lieu of the rapid economic growth in the pacific rim, and the increased production cost, Nike has moved more into countries such as Vietnam and China where the labour is cheaper and labour laws less stringent. (VLF, VN Fact Sheet) Nike does not own any of the factories that produces its products in Asia, and subsequently they do not directly employ the workers or management. They contract out work to factories that make all of the products and run all of the factories. They do, however, have a massive amount of leverage when dealing with these factories because of the huge contracts they supply. To ensure good labour practices, Nike has a Code of Conduct that every contractor must agree to abide by in order to get a contract. The Conduct Code in theory condemns and prohibits child labour, requires that workers be paid fair wage, imposes caps on the days and hours a worker can be forced to work, prohibits mistreatment or discrimination of workers in any form, obligates factories to implement programs that benefit worker's health and safety, and recognizes and respects the workers right to freedom of association. There are 1000 Nike employees worldwide monitoring operations at the subcontractors and specifically the Code of Conduct adherent. The most consistent criticism of Nike is that the workers in the factories contracted by them are not aware of the Code of Conduct that was agreed upon, and/or it is not enforced (especially the wages and overtime aspects) by the factory officials. Critics contend that the factories pay less than minimum wage at times, force too many overtime hours, and fail to make the workplace as clean and as safe as standards dictate. Many of the factories that are contracted have workers and management from different countries, causing some problems in communication. Some factories in China have Taiwanese Managers while factories in Vietnam have Korean managers. This is one reason offered by Nike in defense of the factories failure to comply with the Code of Conduct. To look into this issue, earlier this year Nike commissioned Andrew Young, a former civil rights leader and United Nations ambassador to do an analysis of how well the Code was working. Young and his staff visited four factories in Vietnam, Indonesia, and China for three to four hours each led by Nike's people. Young's conclusion proved not only to be uninformative, but somewhat aggravating to the public due to its elementary tone. "Nike is doing a good job, but could do better" was the statement released by Young at the end of the report. Another aspect of the inquiry that bothered the public was

Monday, November 25, 2019

James Wright and the Invention of Silly Putty

James Wright and the Invention of Silly Putty The plastic putty known as Silly Putty ®Ã‚  has been entertaining youngsters and providing them with innovative playtime since the 1940s. Its had an interesting history since then.   The Origins of Silly Putty ® James Wright, an engineer, discovered Silly Putty ®.  Just as with many awesome inventions, the discovery happened by accident.   Wright was working for the U.S. War Production Board at the time. He was charged with finding a substitute for synthetic rubber that wouldn’t cost the government an arm and a leg to produce. He mixed silicone oil with boric acid and found that the compound acted very much like rubber. It could rebound almost 25 percent higher than a normal rubber ball, and it was impervious to rot. Soft and malleable, it could stretch to many times its original length without tearing. Another of Silly Putty’s ® unique qualities was its ability to copy the image of any printed material it was pressed upon. Wright initially  called his discovery  Ã¢â‚¬Å"Nutty Putty.†Ã‚  The material was sold under the trade name Silly Putty ® in 1949 and it sold faster than any other toy in history, registering over $6 million in sales in the first year.   The Government Wasn’t Impressed Wright’s amazing Silly Putty ® never found a home with the U.S. government as a substitute for synthetic rubber. The government said it wasn’t a superior product. Tell that to millions of kids pressing globs of the stuff onto comic  pages,  lifting images of their favorite action heroes. Marketing consultant  Peter Hodgson didn’t agree with the government, either. Hodgson bought the production rights to Wrights bouncing putty and  is credited with changing the name of Nutty Putty to Silly Putty ®, introducing it to the  public at Easter, selling it inside plastic eggs. Silly Putty’s ® Practical Uses Silly Putty ® wasn’t initially marketed as a toy. In fact, it pretty much bombed at the 1950 International Toy Fair. Hodgson first intended  Silly Putty ® for an adult audience, billing it for its practical purposes.  But despite  its ignoble beginnings, Neiman-Marcus and Doubleday decided to go ahead and sell Silly Putty ® as a toy and it began to take off. When the  New Yorker  mentioned the stuff, sales bloomed – more than a quarter million orders were received within three days. Hodgson then reached his adult audience almost by accident. Parents soon discovered that not only could Silly Putty ® lift perfect images off comic pages, but it was pretty handy for pulling lint off of  fabric as well. It went to space with the Apollo 8 crew in 1968, where it proved effective at keeping objects in place in zero gravity. Binney Smith, Inc., creator of Crayola,  purchased Silly Putty ® after Hodgson’s death. The company claims that more than 300 million Silly Putty ® eggs have sold since 1950. The Composition of Silly Putty Although you probably don’t want to go to the trouble of whipping up a batch at home when you can simply buy some, the basic ingredients of  Silly Putty ®Ã‚  include: Dimethyl Siloxane: 65 percentSilica: 17 percentThixotrol ST: 9 percentPolydimethylsiloxane: 4 percentDecamethylcyclopentasiloxane: 1 percent  Glycerine: 1 percentTitanium Dioxide: 1 percent It’s a safe guess that Binney Smith aren’t divulging all their proprietary secrets, including the introduction of a wide array of  Silly Putty ®Ã‚  colors, some that even glow in the dark.

Thursday, November 21, 2019

The Movie Winnie Mandela Review Example | Topics and Well Written Essays - 750 words

The Winnie Mandela - Movie Review Example A terrorist also depicts a person using terror, intimidation, and violence to achieve an end. The presence of different definitions and understanding of terrorism depicts several levels of complexities in terrorism. The study aims at reviewing the levels of complexities in the film, Winnie Mandela that aimed at expounding the role played by Winnie Mandela in the fight for South Africa’s fight for freedom. There are several ways in which the film, Winnie Mandela portrays terrorism with the definition evident from watching the film being the use of violence or threat of violence to achieve an end. One of the designations of terrorism evident in the film, Winnie Mandela, is violence against others as a measure of achieving a cause. This is evident when Winnie Mandela played by Jennifer Hudson perpetrates violence against opponents. The implication of Winnie Mandela of a teenager’s murder is a designation of terrorism since the main reason for the murder is to send a message to dissenters and informers who would face death and other forms of violence. The film provides that terrorism involves the use of violence to achieve a cause, which in the case of Winnie was to oppose the government through using violence against those who opposed her and the Mandela United Football Club. The use of violence in the achievement of the aim evidences terrorism as aimed at achieving the intended aim using all means necessary. The statement, â€Å"with our boxes of matches and our necklaces, we shall liberate this country†, depicting the use of old tires on informants’ necks and burning them alive depicts violence. Terrorism is also designated as an act of defiance aimed at achieving the goals designed despite the consequences. The film uses the actions of Winnie Mandela to depict defiance through her decision to engage in violence against her deserters. The decision is contrary to the requirements and believes of her husband Nelson Mandela and is well

Wednesday, November 20, 2019

The Federal Reserve Bank Research Paper Example | Topics and Well Written Essays - 1500 words - 1

The Federal Reserve Bank - Research Paper Example ng saving money foundations, keeping up the steadiness of the budgetary framework and giving monetary administrations to depository organizations, the U.S. government, and foreign official establishments. This paper explores numerous issues such as the history, purposes, structure and the available tools for the Fed. The Fed traces its inceptions to 1791, when Congress urged the Treasury Secretary, Alexander Hamilton to establish the first U.S. bank. The first bank was headquartered in Philadelphia; the bank was given a twenty-year contract; however, numerous agrarian-minded Americans were uncomfortable with the ideology as they suggested this would affect the management of the central bank. They decided to restrict it, but the Congress declined through a single vote, and it was renewed in 1811 (Paul, 1996). Congress later created a national bank in 1816, in light of the expansion that came about because of the increment in banknotes printed to pay off the obligation occasioned by the War of 1812. Somewhat more than ten years after its opening, nonetheless, the new bank came into the line of sight of Andrew Jackson, who attempted to slaughter it after he was chosen president in 1828. After the second bank collapsed, state-sanctioned and uncharted â€Å"public banks† flourished. These banks issued their own notes, redeemable in gold or silver. Given that the National Banking Act, passed in 1863, attempted to provide a measure of cash strength, bank runs and money related frenzies stayed necessary into the mid-twentieth century. This was an episode of theory on Wall Street that bottomed out in 1907 (Paul, 1996). The advanced Fed follows its establishing to President Wilson, who came up with a group of counsels that created the proposition which eventually turned into the Federal Reserve Act, passed by Congress in 1913. The seven unique individuals from the FRB sit for a gathering representation, soon after being confirmed. They incorporate the first Chairman of the

Monday, November 18, 2019

Organisational Behaviour Essay Example | Topics and Well Written Essays - 1500 words

Organisational Behaviour - Essay Example Organisational Behaviour is a vast subject, catering to studies pertaining to employees; their motivation strategies, their productivity, their dedication to the organisation they work in, their emotional complexities, the role of workplace environment and peers. Indeed Organisational Behaviour is a detailed research-based subject for determining the factors influencing workplace settings and employees and how to increase their productivity. Hence, for organisational welfare, the knowledge of organizational behavior is unquestionably important. Traditional Organisational Behaviour theories, or initial theories, had been sufficient to cater to the traditional organisational settings. Originally, before the technological advent of computers and the never ending internet connectivity, organisations meant a workplace divided into numerous cubicles with the employees milling about their regular office chores, only leaving their cubicles during lunchtime, and at times working overtime thro ugh the night in their respective offices. Supervision was generally done by observing the employee performance through the tinted cubicle glasses, providing assistance and motivation on spot. However, with rapid technological advancements in the form of software developments and easily available internet connectivity, the typical meaning of â€Å"organisation† and â€Å"workplace† has also evolved. Dictionary.com now defines ‘organisation’ as â€Å"a business or administrative concern united and constructed for a particular end†, with no reference to the physical aspect of the organisation. Technological advancements has made â€Å"work-from-home† possible, just as â€Å"carrying office around† is possible due to the development of gadgets. People do not spend night time working in offices, and most organisations do not have an office space for all their employees – â€Å"working at a distance† has gained popularity as a part of increasing efficiency and cost-cutting strategies of all businesses. This has posed significant challenges to the traditional organisational behaviour theories, posing contemporary issues evolved due to the change in work environments. Firstly, due to technological developments, work can hardly be uniquely distinguished from life. Organisations have undergone immense structural reforms like de-layering, outsourcing, atomisation, casualisation, horizontal linkages, devolution etc. (Murray, Poole & Jones, 2006, p.18-19). Each of these reformations have caused a change in organisational and employees’ behaviour and hence posed challenges to the organisational behaviour theories. De-layering implies the elimination of middle level management due to technical support, flattening the organisational structure of hierarchy and increasing lower level management coordination directly with the top-level management (Murray, Poole & Jones, 2006, p.18-19). Traditionally, middle le vel managers have served the purpose of buffering the communication between the upper and lower levels of management. Outsourcing implies part of an organisation’s value chain being produced by other organisation collaboratively (Murray, Poole & Jones, 2006, p.18-19). This phenomenon has recently spring to light after the worldwide economic crisis

Friday, November 15, 2019

Dangers of Escalation of Commitment in Accounting

Dangers of Escalation of Commitment in Accounting This report analyses the issue of escalation of commitment to a course of action from the perspective of the pharmaceutical industry. Escalation can be defined as a situation where a failing venture is supplied with additional resources beyond the point of feasibility. As such, escalation carries substantial dangers for organisations by generating avoidable economic losses. The report inquiries into the generic causes of escalation by examining subject literature. Accordingly psychological, social, organisational and project-specific factors are identified as common escalation activators. Exploration into the particulars of the said industry categorises profitability issues, market performance concerns, maturing products portfolio alongside development pipeline conditions as features amplifying pharma companies vulnerability to escalation. The point is supported by real-life case examples located in the appendix. Appreciation of escalation causes allows for development of effective prevention policies. The report suggests preventive measures aimed at reducing the occurrence of escalation triggers, such as challenging the individual and social causes. Approaches for reducing other factors impact on decision-making are outlined in the form of strategy alteration as well as process management policies. The report finalises with suggestions on escalating situations management. Statement of Reference The aim of this 2000-word report is to inquiry the causes and dangers of escalation of commitment to a course of action from the perspective of pharmaceutical companies. This report is to assess the dangers of escalation of commitment to a chosen course of action through the perspective of pharmaceutical companies. In order to achieve the aim set, the paper first analyses the definition and threats arising from the phenomenon of escalation. Next, following the framework proposed by Ross Staw (1993) generic causes of escalation are summarised. Subsequently, the report looks at industry- and drug development-specific escalation triggers in an attempt to identify why the pharmaceutical companies are particularly vulnerable to the dangers of escalation of commitment. Then, escalation prevention provisions organised around tackling previously identified triggers are outlined. The report concludes with suggestions concerning the issue of escalating situation management. Escalation of commitment: Definition and dangers Escalation can be defined as a situation where an individual over-commits resources to a failing venture after receiving negative feedback on its performance. Having an option to discontinue, the decision-maker forgoes rational behaviour and devotes more money, time or effort in a false belief that greater involvement will bring the project to successful completion (Staw, 1981). Some examination suggests that escalation as such should not be automatically assigned negative connotation. Low level of employee commitment is also damaging to organisational performance; background factors might justify over-commitment (Heath, 1995). Another view assumes escalation to be a natural feature of the business decision-making that should be treated as an unavoidable expense (Bowen, 1987). The dominant notion supported by extensive research suggests that escalation of commitment should be acted against (Brockner, 1992) because of carrying dangers of: Ultimately leading to multiplication of avoidable losses; Introducing irrational decision-making; Undermining the basic premise of business activity: to maximise gains with minimal costs; Generating substantial opportunity costs Consuming unrecoverable resources, such as time. Appreciation of escalation triggers allows for development of efficient prevention methods aimed at reducing the occurrence of such factors, subsequently protecting the company from the aforementioned detriments. Generic causes of escalation Psychological Initial research suggested that escalation arises primarily from the natural incline of the human being to self-justify behaviour. Supplying the course of action with additional resources serves as unconscious defence technique: the individual reassures him/herself that the original decision made was rational (Staw, 1976). Self-justification need is heightened if the decision-maker holds responsibility for the resource allocation (Staw, 1981), which is typical for investment decision setting. Prospect theory applied to escalation suggests that self-justification is not vital prerequisite for its occurrence. Escalation is induced by the decision-maker using a frame to make decisions under conditions of uncertainty of results. The decision-maker views subsequent decisions in reference to outcomes of initial judgements in order to produce a coherent frame. The negative feedback on the initial resource allocation results in the subsequent distribution being viewed as a choice between definite and possible loss, or a negative frame. Subsequently individuals are prone to escalation by becoming risk-seeking: failing to accept a definite loss even at the cost of incurring greater in the future (Whyte, 1986). How the decision-maker perceives incurred costs, constitutes another escalation trigger (Garland Newport, 1991). Following prospects theory, the sunk costs effect suggests that costs incurred viewed in relation to the total expenditure induce a negative frame, leading to escalating behaviour. Linked with that, the dislike of waste provides another motivation to supply the course of action further, rather than face a definite loss (Arkes Blumer, 1985). Interestingly, excitement about the project outcomes (Schmidt Calantone, 2002), and sunk-time effect ­ (Navarro Fantino, 2009) aid escalation occurrence. Social Importantly, the aforementioned need to justify the correctness of behaviour is not limited to the individual and applies to the wider social context (Staw, 1976). Maintaining an image of a consistent decision-maker among peers proves equally, or more, important to meeting self-justification needs. The desire to obtain social approval is exacerbated under insecurity of the social status in the group, or in a presence of an adverse crowd (Staw, 1976). In such instances the individual is likely to model his/her behaviour to reproduce the model endorsed by the audience (Brockner, 1992). As the group replicates leader stereotypes that emphasize the need for decision-makers to be consistent in actions in order to be perceived as competent (Staw Ross, 1980), the individual aspiring to achieve consistency with the stereotypical image will over-commit not to distort others belief in their leadership potential, and to reaffirm position in the group structure. Intra- or inter- group competition can indicate escalation. The focus is shifted away from objective assessment of the possible outcomes of a chosen decision onto the motivation to win. The need to do whatever it takes to get a step ahead of the competitors introduces scope for irrationality and escalation as such irrational behaviour is common to both of the parties involved (Bazerman, 2006). Organisational Projects receiving strong organisational support are prone to escalation (Pfeffer, 1981 in Ross Staw, 1993), as the decision-makers identify them with the existence of organisation itself. Furthermore, the centrality of the project to organisational values and its entrenchment in the organisational structure account for the projects being continued despite reservations (Goodman et al., 1980 in Ross Staw, 1993). Unwinding the supporting infrastructure might threaten the very basis of working organisational structure; induce change that is often associated with risks and dangers. The costs of acceptance of status quo are perceived as minor to the potential dangers of modified environment. Maintaining reputation and consistency between values and actions prove to constitute forces inducing over-commitment from organisational perspective (Ross Staw, 1993). Companies having publicly announced success might be more hesitant to admit failure and discontinue with the course of action. Project-specific High development costs and risky market performance of the finished product, the acceptance of failures and losses as a feature of the RD process, and reluctance of decision-makers to emotionally detach from the prolonged projects account for greater escalation exposure of RD projects (Schmidt Calantone, 2002). Low potential reusability (Staw Ross, 1993) of the generated output results in reluctance to discontinue the venture in order to avoid waste. Negative framing induces the perception of exit costs, such as compensation packages as definite waste, leading to escalation. The advancement of the project on a timeline constitutes another threat due to sunk-cost effect (Navarro Fantino, 2009). Projects reaching advanced stages of development would be discontinued reluctantly because of accumulation of used resources, including time, and the perception of imminent availability of the anticipated gains. Industry-specific Escalation Triggers Profitability issues Recent data suggests that pharmaceutical companies are to face decline in profit figures in forthcoming years (Datamonitor, 2010). This can be attributed to steadily increasing drug development costs: the costs producing the final product exceed $1 billion, with as few as 20% of successful product entries achieving the break-even point (Innovation.org, 2010). Estimates suggest that pharmaceutical companies should launch two to four drugs annually to maintain steady profit margins (Gassmann Reepmeyer, 2005). However, due to high attrition rates the overall success of organisations strategy is often reliant on the success of a single project (Kola Landis, 2004). These factors pressurise the companies to continue with projects and disregard arising reservations to maintain profitability. Maturing product portfolio The reduction in new component approvals can be partially attributed to strengthening drug registration requirements. Other explanation lies in the controversial innovation deficit experienced by the industry (Schmid Smith, 2004). Lower innovation figures account for pharmaceutical companies being faced with maturing product portfolio. Consequently, the companies engage in a variety of innovative projects overly-optimistically assessing their revenue potential, failing to discontinue when reservations arise. Eventually, the companies face greater losses as the projects fail to generate anticipated revenues, but incurring avoidable losses (Appendix: Dimebon case). Concerns for market performance The pressure to persist is further reinforced by the need to be consistent with companys vision (Ross Staw, 1993). Endorsing the projects demonstrates consistence with the mission statement; reaffirms the reputation as well as reassures the market and investors on following the profitable trail. However, forgoing ethical and safety aspects of drug delivery over concerns for market performance and cost-cutting proves detrimental (Appendix: GSK Puerto Rico Plant). Development pipeline conditions The specificity of the drug development pipeline further adds to the vulnerability to the dangers of escalation of commitment. The drug development time is estimated to surpass 10 years, with the costs amplifying as the project progresses (Accenture, 2007). This suggests heightened emotional attachment and excitement towards results, as well as existence of supporting infrastructure as powerful motivators of escalation. Attrition figures reveal that escalation is common in the industry as the most projects are withdrawn after reaching the most cost intensive stage of advanced clinical trials that precedes the registration process; or are recalled after reaching the patient due to safety concerns that have been ignored earlier on (Kola Landis, 2004) (Appendix: Avandia case). Escalation: how to prevent it? Tackling individual and social causes Perhaps introduce appraisal procedures emphasizing ones ability to build on past actions, rather than progression of the project. This will reduce managers fear of negative consequences if the project fails. Confidential treatment of sensitive matters, such as personal failures, will reduce the reputation retention motivation for escalation (Simonson Staw, 1992). Consider developing positive leader stereotypes supported by convergent organisational values emphasizing the rationality of decision-making. Furthermore, introducing panel decision-making procedures contribute to preventing escalation by reducing individual responsibility for the decision taken (Simonson Staw, 1992; Schmidt Calantone, 2002). Inviting members of relevant departments allows for assessing the projects success potential from a variety of angles limiting scope for escalation to arise. Ponder developing neutral decision frames by rotating managers in charge of the project so that different individuals held responsibility for initial and subsequent resources allocations (Simonson Staw, 1992). Additionally, foster for emotional detachment from sunk costs by introducing training in mental budgeting (Heath, 1995). Project evaluation and management Clear and achievable targets should be set out at the project initiation alongside exit points at various stages of progression (Schmid Smith, 2004). Measuring projects performance against set aims; assessing the efficiency with which resources yield results at the selected points allows for early estimation whether the project is following the anticipated pathway, thus allowing to avoid greater losses. Consider adopting attrite early strategy (Schmid Smith, 2004) as companys motto. Consider participation in multi-stakeholder analysis projects evaluating the potential value of innovative drug projects at early stages of development such as the consultations conducted within the European Healthcare Innovation Leadership Network (AstraZeneca, 2010). Ponder involving external parties in the project (Schmidt Calantone, 2002). Perhaps engage auditors to assess the success projects success potential at its outset or to devise effective contingency planning. This will ensure objectivity and independence of organisational politics. Consider outsourcing the project to subcontractors to avoid its institutionalisation in the organisational structure. Alternating middle-to-long-term strategy Consider renewing existing product portfolio and engagement in me-too drug developments. This ensures steady revenue generation from inelastic demand segments (Ganuza et al., 2009) and carries less risk comparing to reliance on anticipated gains from innovative compounds. Estimations suggest that involvement in drug-related sectors or focusing on advancement in licensed compounds constitute a potentially profitable alternative (Schmid Smith, 2004). Consider GSKs involvement in healthcare brands as an example. Managing Escalation Suppose the escalating situation arises, consider replacing the project manager or establishing panel assessment in order to remove the negative thinking frame, rid off the potential self-justification needs and assess realistically projects success potential (Simonson Staw, 1992). Consequently, ponder engaging external consultants to develop plausible solutions and introduce other point of view independent of the political and organisational influence. Otherwise, evaluate potential salvage value of the project towards establishing uses other than the initial one anticipated (Appendix: Viagra case). Furthermore, consider whether external financial support for advanced research is available; and if is feasible to use towards accomplishment of the projects aims. Otherwise, ponder engaging in partnership with a company undertaking research in similar compound in order to combine knowhow and reduce costs. Appendix Avandia case Recent withdrawal of GSKs highly innovative and best-selling diabetes drug, Avandia, in EU was caused by the linkages with deaths by heart failures among the patients on the medication (FT.com, 2010b). Allegedly, the company was aware of the severity of adverse effects, however launched the drug to the market (Avandia Recall News, 2010). Estimations suggest that GSK could face between $1.1bn and $6bn in compensation costs (FT.com, 2010a) that could have been avoided had the company ceased the project when safety concerns were brought to light. Additionally, bad publicity incurred after the allegations surfaced resulted in fall of GSK share prices, and the company facing negative profit accounts (FT.com, 2010c). Dimebon case Pfizer has recently withdrawn from advanced clinical trials (undertaken in partnership with Medivation) of highly anticipated Alzheimers disease cure, Dimebon, after the drug exhibited no promising therapeutic results (MedScape Medical News, 2010). The reservations about the curative properties of the compound have been raised at early stages of the process. It is assumed that the logic behind Dimebons miraculous effects was never properly investigated. Furthermore, similar compounds failed in previous trials (ABC News online, 2010). Escalating behaviour in such case could be linked to Pfizer losing patent rights the currently marketed Alzheimers treatment, Aricept and was in need of a profitable replacement. As a result of failure to investigate and evaluate promptly, Pfizer has incurred $725 million in RD costs (the Economist.com, 2010). GSK Puerto Rico Plant case GSK is reported to pay $750m in penalty payment to US government and other claimants following allegations on manufacturing malpractice and failure to adhere to safety standards in production plant in Puerto Rico. The allegations regarding mal-adjusted doses of active ingredients and ineffectiveness of drugs submitted to government programmes were revealed by a former employee and resulted in the company being charged with a criminal offence (Wall Street Journal Law Blog, 2010). Viagra case Initially Viagra was developed as a cordial drug aimed at decreasing blood pressure and preventing cardiac arrests. Clinical trials unexpectedly revealed potentially exploitable and marketable properties of the drug: high effectiveness in fighting erectile dysfunction in men. In the six months following its launch as a revolutionary treatment, in 1998 Viagra worldwide sales have exceeded  £300 million (BBCnews.com, 1999).

Wednesday, November 13, 2019

Critical Response- George Orwells Shooting And Elephant :: essays research papers

Critical Response Essay I class, we read a short story by George Orwell called Shooting an Elephant. It was a story about courage, judgment, and the pressure of peers. I personally did not like this story. I found it boring, pointless, and just another "hasn’t -this -happened -to -you" story about nothing. However, it was very well written, and if I had to critically respond to this story, I would praise the author on a number of things. The story opens by describing the relationship between the town and himself, a sort of sub-division police officer of the town. Description is definetly not lacking in the opening, as words such as "aimless", and "petty" are used to describe the town, and the way it treats it officers. It descriibes the kind of ignorance the town has to outsiders and anyone they do not "approve of". The story opens well, and clarifies right away, the who, what, where, when, why and how. No questions are asked and all confusions are quickly abolished. The second paragraph describes very vividly how he the narrator feels about his job choice, and his views on the village. He says "†¦I was stuck between my hatred of the empire I served and my rage against the evil-spirited little beasts who tried to make my job impossible". The narrator not only is in a place where he hates, but he also hates the people he works with, and works for! Wow, how’d he end up there? Basically, the story line goes along to tell the tale of an elephant that needs to be killed, because it got out of the zoo and endagers the community. The story describes how the main character feels about himself and the pressures of the community. A showdown climaxes the storyline between the elephant and the narrator, and the entire village is there to witness and entice the main character. Critical Response- George Orwells Shooting And Elephant :: essays research papers Critical Response Essay I class, we read a short story by George Orwell called Shooting an Elephant. It was a story about courage, judgment, and the pressure of peers. I personally did not like this story. I found it boring, pointless, and just another "hasn’t -this -happened -to -you" story about nothing. However, it was very well written, and if I had to critically respond to this story, I would praise the author on a number of things. The story opens by describing the relationship between the town and himself, a sort of sub-division police officer of the town. Description is definetly not lacking in the opening, as words such as "aimless", and "petty" are used to describe the town, and the way it treats it officers. It descriibes the kind of ignorance the town has to outsiders and anyone they do not "approve of". The story opens well, and clarifies right away, the who, what, where, when, why and how. No questions are asked and all confusions are quickly abolished. The second paragraph describes very vividly how he the narrator feels about his job choice, and his views on the village. He says "†¦I was stuck between my hatred of the empire I served and my rage against the evil-spirited little beasts who tried to make my job impossible". The narrator not only is in a place where he hates, but he also hates the people he works with, and works for! Wow, how’d he end up there? Basically, the story line goes along to tell the tale of an elephant that needs to be killed, because it got out of the zoo and endagers the community. The story describes how the main character feels about himself and the pressures of the community. A showdown climaxes the storyline between the elephant and the narrator, and the entire village is there to witness and entice the main character.

Monday, November 11, 2019

Nature of Probability and Statistics Essay

Descriptive statistics consists of the collection, organization, summarization, and presentation of data. Inferential statistics consists of generalizing from samples to populations, performing estimations hypothesis testing, determining relationships among variables, and making predictions. (Probability, Hypothesis testing, relationships between variables, predictions) Probability is the chance of an event occurring. A population consists of all subjects that are being studied. A sample is a group of subjects selected from a population. Variables and Types of Data In order to gain knowledge about seemingly haphazard events, statisticians collect information for variables that describe the events. A variable is a characteristic or attribute that can assume different values. Data are the values that variables can assume. A data set is a collection of data values. Each value in the data set is called a data value or a datum. Random variables have values that are determined by chance. 1 M227 Chapter 1 Nature of Probability and Statistics Qualitative variables can be placed into distinct categories according to some characteristic or attribute. Quantitative variables are numerical in nature and can be ordered or ranked. Quantitative variables can be further classified into two groups. o Discrete variables assume values that can be counted. o Continuous variables can assume all values between any two specific values. (Discuss boundaries: ex. recorded height of 73 has boundary of 72. 5 ? x < 73. 5 ) Levels of Measurement: Variables are classified by how are organized, counted, or measured: Nominal—classifies data into mutually exclusive (nonoverlapping), exhausting categories in which no order or ranking can be imposed on the data. Ordinal—classifies data into categories that can be ranked; however, precise differences between the ranks do not exist. Interval—ranks data, and precise differences between units of measure do exist; however, there is no meaningful zero. Ratio—possesses all the characteristics of interval measurement, and there exists a true zero. Data Collection and Sampling Techniques Surveys are the most common method of collecting data. Three methods of surveying are: o Telephone surveys o Mailed questionnaire surveys o Personal interviews Direct Observations or surveying records Methods to obtain unbiased samples: o Random samples are selected using chance methods or random methods. o Systematic samples are obtained by numbering each subject of the population and then selecting every kth number. o Stratified samples are obtained by dividing the population into groups according to some characteristic that is important to the study, then sampling from each group. Cluster samples are obtained by using intact groups called clusters. Two main ways to classify statistical studies: In an observational study, the researcher merely observes what is happening or what has happened in the past and tries to draw conclusions based on these observations. In an experimental study, the researcher manipulates one of the variables and tries to determine how the manipulation influ ences other variables. 2 M227 Chapter 1 Nature of Probability and Statistics Statistical studies usually include one or more independent variables and one dependent variable. The independent variable in an axperimental study is the one that is being manipulated by the researcher. The independent variable is also called the explanatory variable. The rsultant variable is called the dependent variable or the random outcome. Uses and Misuses of Statistics Detached statistics Implied connections Misleading graphs Faulty survey questions Computers and Calculators In the past, statistical calculations were done with pencil and paper. However, with the advent of calculators, numerical computations became easier. Excel, MINITAB, and the TI-83 graphing calculator can be used to perform statistical computations.

Friday, November 8, 2019

The People Leisure and Cultures of Blacks During the HArlem Renaissance essays

The People Leisure and Cultures of Blacks During the HArlem Renaissance essays The People, Leisure, and Culture of Blacks It seems unfair that the pages of our history books or even the lecturers in majority of classrooms speak very little of the accomplishments of blacks. They speak very little of a period within black history in which many of the greatest musicians, writers, painters, and influential paragon' emerged. This significant period in time was known as the Harlem Renaissance. Blacks attained the opportunity to work at upper-class jobs, own their own homes, and establish status among themselves. To no ones surprise, they still were not accepted into the so called upper-class of white society, but they neither worried nor became distressed over the fact. They created societies of their own which opened doors for blacks to attain opportunities that were absolutely unheard of, just before the Renaissance. It was from this same society where the beautiful melodies of jazz emerged. Colleagues and peers of their own race, which created a powerful bond between them, accepted Blacks. The at titudes which prompted the movement were those that came about because of the beginning of : (1) the nationalist tendencies of the time, (2) the movement of black Americans from slavery to freedom and from rural to city living, (3) Afro- Americans renewed pride in their African heritage, and (4) the influences of the period bounded by the close of the Civil War and the economic collapse of the 1930s. From education, to the stage of Broadway, to music, and to a revived race, blacks possessed more intelligence, talent, and ingenuity then they will ever be given credit for and it all began with the Harlem Renaissance. The Harlem Renaissance, also known as the New Negro Movement, was the greatest of literary periods in which creativity and vehemence were clearly expressed. Literature was no longer a white write looking at the black experience from his/h...

Wednesday, November 6, 2019

A System Analyst essays

A System Analyst essays A Systems Analyst analyses, designs and implements the information gathered previously to a system, the final product which is a report of yearly sales, profits, etc. The first thing a Systems Analyst does is to interview the company which wants the report, (called the user) to find out what kind of report they want, format, etc. They must find whether the report is feasible or not, and to find out, they do an analysis of the project. To analyze the project, they must find out where are they going to get the information, how, when is the project going to be done, etc. They then design the system, which is to make a 'skeleton' of the project. They write specifications, of what is to be in the final report. They do flowcharting, specifications for the programmers of the report, and development control. Development control is where the Systems Analyst works with the programmers along a critical path. A critical path is like a due date, if the report is to be done in thirty days, the Systems Analyst makes sure the report is done in thirty days. The Systems Analyst also follows the first analysis of when the project will be finished. The critical path also calculates how many man hours it will take to finish, etc. A critical path flowchart also helps the programmers along. After the development is finished and a prototype of the report is finished, the Systems Analyst helps the programmers in testing the program for bugs. This is similar to quality control. The Systems Analyst helps to makes sure the work is done until the final report is achieved. Once the final report is finished and free of bugs, it is sent to the user. The Systems Analyst has a big job to do, he/she is responsible for the design, the development, and implementation of the report, ie: what purpose will it serve, presentation, etc. The Systems Analyst creates and helps finish the final product, making all the specifications and charts for what ...

Monday, November 4, 2019

Alternate Universe Essay Example | Topics and Well Written Essays - 1250 words

Alternate Universe - Essay Example After what felt like three and a half years, the numbness eased. I was not even aware as to why that was happening. Everything around me was white. So pure, so serene and tranquil, yet I felt like screaming. I felt trapped; Trapped because of my own deeds. I didn't even know what I had done to deserve this. My brain reverberated against my skull. My limbs hurt. My voice was not even soft enough to be heard by ultrasound-sensitive animals. Suddenly, three people clad in white lab coats entered the high-ceilinged room. They were talking in hurried whispers. At that point, the only sound that I could hear was my beating heart, running faster than a bullet train; almost feeling like it was going to leap out of my chest. Despite this, there was some sort of assurance about those three beings; I didn’t know who they were, however, it didn't feel like it was going to get worse. On the contrary, I felt like I was going to be out of that place soon. In fact, all I wanted was to be back within the safety of my bed and warm blanket; even to be with my family and hug them. I hadn’t felt these emotions in a long time, and it was astonishing to watch myself repent on the paucity of time that I had spent in that aspect of my life. The three, individuals in lab coats, seemed to be emanating a warm aura. I needed the assurance more than anything especially at that point in time because despite being confident, my heart wasn't convinced enough. It thumped fast. It beat against my chest.... On the contrary, I felt like I was going to be out of that place soon. In fact, all I wanted was to be back within the safety of my bed and warm blanket; even to be with my family and hug them. I hadn’t felt these emotions in a long time, and it was astonishing to watch myself repent on the paucity of time that I had spent in that aspect of my life. The three, individuals in lab coats, seemed to be emanating a warm aura. I needed the assurance more than anything especially at that point of time because despite being confident, my heart wasn't convinced enough. It thumped fast. It beat against my chest. I could hear my heartstrings come undone. It felt as if my aortic pump wanted to leap out of the sole window in the room, and reach out to the world that was waiting for me. The hushed voices used the word death way too many times to even fit the few sentences they muttered under their breaths. They appeared to have a mini squabble of some kind. There was a woman among the three people, and there was some sort of joy that I got by knowing that; her voice was very much like my mother’s voice; mellifluous. I could almost imagine her break into a sing-song with her words; but then again my brain was acting fuzzy and I wasn’t thinking right. She couldn’t be my mother; whatever would my mother be doing in a place like this?! The woman, nevertheless, knew that I was safe and alive. I had a strong sense, she did. She kept providing the men with a clear indication regarding the same thought and stopped them twice from reaching out to me. They were so far, yet so close. But something told me I was going to make it. Make it where? That, even I didn’t have

Saturday, November 2, 2019

Immigration In The US Essay Example | Topics and Well Written Essays - 1000 words

Immigration In The US - Essay Example   The constant acculturation causes a hybrid culture as both minority and majority culture traits are fused together while assimilation assumes a majority static culture that has to be adopted by smaller ethnic groups but discounts the influence of small ethnic groups on the majority culture.  Pluralism encourages group diversity along with maintenance of group boundaries and can be seen as opposed to assimilation. Structural pluralism holds that segregated communities exist within the larger cultures who conduct social relations internally through localized institutions. In contrast, liberal pluralism allows the individual to choose how pluralist one wants to be such as many people associate with ethnic traits and practices generations after immigration. The resistance by Euro-Americans is available as evidence of pluralism such as by marriage within local groups only.  Transnationalism is the creation of combined plural civic and political memberships, economic involvements, social networks and cultural identities which link people and institutions in more than one diverse nation state in a multi-layered pattern. Immigration in the late nineteenth and early twentieth century’s created a back and forth movement of immigrants who helped move cultural values across borders through effective means of communication and transport. Such immigrants developed trans-local boundaries in order to protect the ideas of citizenship and belonging to their mother countries. Changes in the early twentieth century ensured that immigrants developed a plural identity in America and their mother state’s without fear of opposition. The present day transnationalism is far more diverse and encompasses private and public spheres of operation. Second generations of transnational immigrants display mobility in parental ethnic groups as well as in America society. The best method for immigrants to adapt to the host society derives through a combination of pluralism an d transnationalism. Immigrants cannot be expected to revoke their ethnic, cultural and religious ties to the mother country within a few short years of arrival in the host country. Instead the immigrants hold onto their identities in the form of transnatinoalism while the host society has to display pluralism in order to make the immigrants more accepted in society. The use of assimilation would on the other hand lead to friction between immigrants and host societies as a revocation of values is deemed necessary for cultural integration. Do women have more to gain or more to lose from migration (for instance, compared to men)? You can think about this issue in terms of the causes of migration, the relative difficulty/ease of migrating for women, the occupational and economic status of women migrants in the host society, or the impact of migration on women’s social status within the family/household. Women like men stand to gain and lose at the same time due to immigration but their losses are considerably greater than those experienced by men.